When a person bleeds, their platelets are critical in stopping that bleeding. This is called coagulation. Coagulation is the process by which the blood forms clots. Platelet disorders are rare, occurring in less than 1 in 1 million people. There are several types of platelet disorders:
Bernard-Soulier syndrome: Is an inherited disorder in which platelets are deficient in glycoproteins, making the platelets unable to bind to blood vessel walls and collect at the site of an injury to stop bleeding.
Gray Platelet syndrome: The platelets of a person with gray platelet syndrome lack the ability to store proteins in alpha granules, making it difficult for their blood to clot.
Delta Storage Pool Disease: This disorder slows the ability of platelets to activate coagulation as well as the ability to constrict blood vessels.
- Platelet storage pool disorder: Platelets have storage pools to store substances that are released when a platlet plug needs to be created. This disorder exists when the platelets have faulty storage for these substances. This disorder is also called platelet secretion disorder.
Glanzmann thrombasthenia: A disorder characterized by a deficiency of platelets to clump together to form a clot.